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. 2019 Jul 2;39(7):BSR20181852. doi: 10.1042/BSR20181852

Figure 3. Expressions of CRP, IL-6 and ICAM by qRT-PCR and Western blotting.

Figure 3

Tail veins of STZ-induced model (n=30 and 5 mice died or were not successfully modeled during STZ induction) rats were injected with liposomes containing different sequences (miR-15a-5p mimic, miR-15a-5p inhibitor or FASN shRNA) threee times a week for 4 weeks. After 4 weeks, the thoracic aortas of each group (n=6 for each group) of rats was isolated and used to detect the expression of CRP, IL-6 and ICAM. (A) mRNA expressions of CRP, IL-6 and ICAM; (B) band patterns of Western blot of CRP, IL-6 and ICAM. (C) Protein expressions of CRP, IL-6 and ICAM. *, P<0.05 compared with NC group. Data shown are mean ± SD, experiments had been repeated three times, @, P<0.05 compared with miR-15a-5p mimic + sh-FASN group.