Table 3.
Correlation between the level of biofilm formation and antibiotic resistance in 65 S. epidermidis isolates
| Antimicrobial category | Antimicrobial agent | Optical density570 | P-value | |
|---|---|---|---|---|
| Susceptible | Resistance | |||
| Gentamicin | 0.166 (0.260, 0.534) | 0.230 (0.090, 0.119) | <0.001 | |
| Aminoglycosides | Tobramycin | 0.270 (0.138, 0.443) | 0.215 (0.065, 0.100) | <0.001 |
| Amikacin | 0.120 (0.097, 0.254) | 0.312 (0.063, 0.100) | <0.001 | |
| Ansamycins | Rifampin | 0.150 (0.156, 0.479) | 0.142 (0.188, 0.113) | <0.001 |
| Ciprofloxacin | 0.138 (0.123, 0.456) | 0.200 (0.088, 0.120) | <0.001 | |
| Fluoroquinolones | Levofloxacin | – | 0.376 (0.188, 0.169) | <0.001 |
| Azithromycin | – | 0.200 (0.088, 0.117) | <0.001 | |
| Macrolides | Clarithromycin | – | 0.303 (0.087, 0.119) | <0.001 |
| Erythromycin | 0.179 (0.100, 0.320) | 0.313 (0.130, 0.375) | ||
| Incosamidesl | Clindamycin | 0.237 (0.404, 0.537) | 0.437 (0.260, 0.498) | <0.001 |
| Folate pathway inhibitors | Trimethoprim/sulfamethoxazole | 0.325 (0.436, 0.145) | <0.001 | |
| Oxazolidinones | Linezolid | 0.118 (0.195, 0.357) | – | 0.455 |
| Tetracycline | 0.196 (0.238, 0.468) | 0.125 (0.085, 0.112) | <0.001 | |
| Tetracyclines | Doxycycline | – | 0.213 (0.087, 0.118) | <0.001 |
| Minocycline | 0.278 (0.010, 0.444) | 0.290 (0.089, 0.121) | <0.001 | |
| Glycopeptides | Vancomycin | 0.178 (0.277, 0.404) | – | <0.001 |