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(A) In vivo fluorescence imaging of A549 tumor-bearing mice administrated with GA and DiR co-loaded nanoparticles with or without pre-injection of free HA at 2 and 24 hrs. (B) Ex vivo fluorescence imaging of tissues including tumor, heart, liver, spleen, lung, and kidney excised from mice after administrated with GA and DiR co-loaded micelles for 24 hrs.
Abbreviations: HA, hyaluronic acid; HECS, hydroxyethyl chitosan; OA, octylamine; GA, gambogic acid.
