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. 2018 Nov 29;34(7):1232–1239. doi: 10.1093/ndt/gfy350

FIGURE 2.

FIGURE 2

Relationship of average urine pellet podocin mRNA in the first year and long-term renal function decline. The figure demonstrates that an increase in the average urine pellet podocin mRNA (UPodCR) in the first year is associated with eGFR decline. As an example, based on the coefficients obtained from the multivariable linear regression model, if the average eGFR of a kidney transplant by the end of the first year is 45 mL/min, then a 10-fold increased UPodCR, such as seen in TG, will be associated with a 7.2 mL/min/year loss in eGFR and thus the graft would be expected to reach end stage in another 4–5 years (eGFR <15 mL/min).