Table 3.

Predictors of increased urine pellet podocin mRNA (UPodCR) in the first 3 months posttransplant (multivariable model)

	β coef.	SE	P-value	LCL	UCL
Recipient:donor BSA mismatch	10.2	5.12	0.05	0.14	20.2
Recipient BSA	5.0	2.58	0.05	0.00	10.1
Donor BSA	−5.7	2.63	0.03	−10.85	−0.52

Initial hypothesis-driven multivariable model was adjusted for donor age, type of kidney (living versus cadaveric), cold ischemia time, donor BSA, recipient BSA and the RD BSA mismatch ratio (as a measure of the workload). In the next steps, nonsignificant variables were removed one at a time, leaving only the significant variables in the mode (backward selection) [38].

Based on β coefficients, a 0.1 kg/m² increase in the donor BSA was associated with a 33% lower UPodCR. In contrast, a 0.1 kg/m² increase in recipient BSA was associated with a 1.4-fold increase in average UPodCR. Similarly, a 0.1 increase in the recipient:donor BSA mismatch ratio was associated with a 2.0. Could write out just as 2-fold increase in UPodCR. Thus, for example, if the recipient BSA was 20% larger than the donor BSA, then one would expect an almost 4-fold increased UPodCR compared with a donor and recipient pair with a similar BSA.

BSA, body surface area (DuBois equation); Coef., coefficient (see text); SE, standard error; LCL, lower confidence limit; UCL, upper confidence limit.