Table 4.

Studies evaluating the association of PR interval with clinical outcomes in CKD

References	Population	Sample size	Follow-up	Results	Comments
Flueckiger et al. [24]	CKD 5 and ESRD evaluated for renal transplantation	930	37.2 months (median)	PR interval was associated with all-cause mortality (HR = 1.97, 95% CI 1.18–3.29; P = 0.090)
Deo et al. [27]	CKD	3939	90 months (median)	PR >200 ms is associated with cardiovascular mortality (HR = 1.62, 95% CI 1.19–2.19)
Green et al. [11]	HD and PD	323	43.2 months (mean)	No independent association between PR interval and cardiovascular outcomes in multivariate analysis
Kestenbaum et al. [40]	CKD	600	110.4 months (median)	No independent association between PR prolongation and incident cardiovascular events
Badarau et al. [38]	HD	116	17.5 months (median)	Log pre- and post-dialysis difference in PR interval predicts cardiovascular events (HR = 0.387, 95% CI 0.251–0.597; P < 0.001)
Silva et al. [39]	HD	100	14 months (mean)	The duration of the PR interval was independently associated with bradyarrhythmias (odds ratio = 1.05, 95% CI 1.02–1.08; P < 0.001)	Candidates for renal transplantation