Table 1.
Clinical characteristics of patients
| Variables | Metastasis site | |||||
|---|---|---|---|---|---|---|
| Brain | Bone | Liver | Lung | multisite | P Value | |
| Gender | <0.001 | |||||
| Male | 6419(58.6) | 4260(51.4) | 2996(52.8) | 4837(51.3) | 11070(54.4) | |
| Female | 4526(41.4) | 4034(48.6) | 2681(47.2) | 4593(48.7) | 9281(45.6) | |
| Age | <0.001 | |||||
| ≤60 | 2994(27.4) | 3027(36.5) | 1321(23.3) | 1982(21.0) | 6447(31.7) | |
| >60 | 7951(72.6) | 5267(63.5) | 4356(76.7) | 7448(79.0) | 13904(68.3) | |
| Race | ||||||
| Caucasian | 8844(80.8) | 6585(79.4) | 4836(85.2) | 7297(77.4) | 16111(79.2) | |
| Black | 1263(11.5) | 1068(12.9) | 580(10.2) | 1268(13.4) | 2353(11.6) | |
| Others | 838(7.7) | 641(7.7) | 261(4.6) | 865(9.2) | 1887(9.3) | |
| Histology | ||||||
| SCLC | 9332(85.3) | 6453(77.8) | 2551(44.9) | 8409(89.2) | 15095(74.2) | |
| NSCLC | 1613(14.7) | 1841(22.2) | 3126(55.1) | 1021(10.8) | 5256(25.8) | |
| Grade | ||||||
| I | 201(1.8) | 112(1.4) | 33(0.6) | 430(4.6) | 289(1.4) | |
| II | 1144(10.5) | 801(9.7) | 254(4.5) | 1314(13.9) | 1680(8.3) | |
| III | 2333(21.3) | 2146(25.9) | 820(14.4) | 2222(23.6) | 4087(20.1) | |
| IV | 320(2.9) | 363(4.4) | 397(7.0) | 228(2.4) | 774(3.8) | |
| Unknown | 6947(63.5) | 4872(58.7) | 4173(73.5) | 5236(55.5) | 13521(66.4) | |
| T stage | ||||||
| T1 | 2696(24.6) | 2110(25.4) | 1118(19.7) | 2003(21.2) | 4088(20.1) | |
| T2 | 2625(24.0) | 2067(24.9) | 1097(19.3) | 2092(22.2) | 4845(23.8) | |
| T3 | 1623(14.8) | 1366(16.5) | 793(14.0) | 1431(15.2) | 3304(16.2) | |
| T4 | 1359(12.4) | 1230(14.8) | 825(14.5) | 1415(15.0) | 2994(14.7) | |
| Tx | 2642(24.1) | 1521(18.3) | 1844(32.5) | 2489(26.4) | 5120(25.2) | |
| Surgery of Metastases | ||||||
| No | 10349(94.6) | 6596(79.5) | 5573(98.2) | 9199(97.6) | 19122(94.0) | |
| Yes | 577(5.3) | 1682(20.3) | 79(1.4) | 216(2.3) | 1199(5.9) | |
| Unknown | 19(0.2) | 16(0.2) | 25(0.4) | 15(0.2) | 30(0.1) | |
| Radiotherapy | ||||||
| Yes | 5362(49.0) | 6399(77.2) | 880(15.5) | 2102(22.3) | 10473(51.5) | |
| No | 147(1.3) | 106(1.3) | 92(1.6) | 194(2.1) | 288(1.4) | |
| Unknown | 5436(49.7) | 1789(21.6) | 4705(82.9) | 7134(75.7) | 9590(47.1) | |
| Chemotherapy | ||||||
| No | 4665(42.6) | 3522(42.5) | 2627(46.3) | 4419(46.9) | 8593(42.2) | |
| Yes | 6280(57.4) | 4772(57.5) | 3050(53.7) | 5011(53.1) | 11758(57.8) | |