Table 1.
Demographic and clinical characteristics for ovarian cancer patients diagnosed with and without bone metastasis.
| Subject characteristics | No. of ovarian cancer patients (2010-2015) | χ2 | P-value | |
|---|---|---|---|---|
| With BM (N=352, 1.09%) | Without BM (N=31826, 98.91%) | |||
| Age, in years | 16.29 | <0.001 | ||
| 18-40 | 20(0.82) | 2413(99.18) | ||
| 41-64 | 151(0.91) | 16417(99.09) | ||
| ≥65 | 181(1.37) | 12996(98.63) | ||
| Race | 8.88 | 0.01 | ||
| White | 283(1.08) | 25963(98.92) | ||
| Black | 45(1.60) | 2767(98.40) | ||
| Others | 24(0.81) | 2939(99.19) | ||
| Unknown | 0(0.00) | 157(100.00) | ||
| Marital status | 7.97 | 0.01 | ||
| Married | 145(0.94) | 15359(99.06) | ||
| Unmarried | 193(1.27) | 14982(98.73) | ||
| Unknown | 14(0.93) | 1485(99.07) | ||
| Insurance | 0.36 | 0.55 | ||
| Insured | 326(1.07) | 30140(98.93) | ||
| Uninsured | 15(1.25) | 1182(98.75) | ||
| Unknown | 11(2.14) | 504(97.86) | ||
| Laterality | 5.01 | 0.08 | ||
| Left | 52(0.63) | 8236(99.37) | ||
| Right | 75(0.87) | 8579(99.13) | ||
| Bilateral | 63(0.62) | 10093(99.38) | ||
| Unknown | 162(3.19) | 4918(96.81) | ||
| T stage | 35.59 | <0.001 | ||
| T1 | 23(0.26) | 8727(99.74) | ||
| T2 | 46(1.07) | 4253(98.93) | ||
| T3 | 129(0.80) | 16097(99.20) | ||
| Unknown | 154(5.30) | 2749(94.70) | ||
| N stage | 74.84 | <0.001 | ||
| N0 | 134(0.59) | 22550(99.41) | ||
| N1 | 111(1.70) | 6426(98.30) | ||
| Unknown | 107(3.62) | 2850(96.38) | ||
| Grade | 20.69 | <0.001 | ||
| Ⅰ | 4(0.17) | 2336(99.83) | ||
| Ⅱ | 7(0.21) | 3331(99.79) | ||
| Ⅲ | 66(0.76) | 8618(99.24) | ||
| Ⅳ | 34(0.54) | 6314(99.46) | ||
| Unknown | 241(2.10) | 11227(97.90) | ||
| Histology | 41.37 | <0.001 | ||
| Serous | 87(0.58) | 14815(99.42) | ||
| Non-serous | 205(1.30) | 15609(98.70) | ||
| Unknown | 60(4.10) | 1402(95.90) | ||
| CA-125 | 6.02 | 0.01 | ||
| Normal | 15(0.52) | 2853(99.48) | ||
| Elevated | 215(0.99) | 21441(99.01) | ||
| Unknown | 122(1.59) | 7532(98.41) | ||
| Lung Met | 642.95 | <0.001 | ||
| None | 207(0.69) | 29879(99.31) | ||
| Yes | 127(6.87) | 1722(93.13) | ||
| Unknown | 18(7.41) | 225(92.59) | ||
| Liver Met | 606.90 | <0.001 | ||
| None | 200(0.67) | 29636(99.33) | ||
| Yes | 136(6.24) | 2043(93.76) | ||
| Unknown | 16(9.82) | 147(90.18) | ||
| Brain Met | 460.19 | <0.001 | ||
| None | 301(0.94) | 31705(99.06) | ||
| Yes | 20(24.69) | 61(75.31) | ||
| Unknown | 31(34.07) | 60(65.93) | ||
| Sur(pri) | 526.89 | <0.001 | ||
| None | 250(3.63) | 6645(96.37) | ||
| Yes | 99(0.39) | 25132(99.61) | ||
| Unknown | 3(5.77) | 49(94.23) | ||
Abbreviations: BM=bone metastases; CA-125 = cancer antigen 125; Met=metastases; Sur(pri)=surgical treatments on primary site.