Table 3.
Univariate cox regression analysis of recurrence-free survival.
| Characteristics | HR | 95.0% CI | p-value |
|---|---|---|---|
| Age | 1.013 | 0.993-1.033 | 0.194 |
| Gender | 1.460 | 0.750-2.845 | 0.266 |
| Histological type | 1.150 | 0.749-1.766 | 0.523 |
| Tumor size | 1.154 | 0.970-1.375 | 0.107 |
| T stage | 1.588 | 1.110-2.272 | 0.011* |
| Unilateral or Bilateral | 1.485 | 0.679-3.250 | 0.322 |
| Multifocal or Unifocal | 1.267 | 0.672-2.389 | 0.465 |
| Thyroiditis | 1.147 | 0.477-2.757 | 0.760 |
| Extra thyroidal invasion | 1.332 | 0.694-2.557 | 0.388 |
| Lymph node metastasis | 1.454 | 0.749-2.821 | 0.268 |
| Metastasis | 8.955 | 2.596-30.897 | 0.001* |
| AJCC stage | 1.528 | 1.167-2.001 | 0.002* |
| AKR1C2 expression (continuous variable) | 0.824 | 0.681-0.998 | 0.047* |
* p-value < 0.05.