Table 5.
Predictive factors investigated in other studies
| Institute | No. | Treatment | Factors been evaluated |
|---|---|---|---|
| HIT 39 | 101 | primary, n=88 recurrent, n=13 |
age, sex, tumor volume, treatment (primary, recurrence) |
| HIT 28 | 56 | primary, n=41 recurrent, n=15 |
age, dose, resection status, sexa, tumor volume, tumor location, treatment (primary, recurrence)a |
| NIRS 9 | 73 | primary, n=55 recurrent, n=17 Metastatic, n=3 |
age, histologya, tumor volumea, tumor location, treatment (primary, recurrence, metastasis) |
| NIRS 29 | 188 | primary, n=188 | dose, level of proximal invasion, sex, tumor volume |
| GSI 35 | 79 | primary, n=54 recurrent, n=25 |
agea, boost volumea, dose, sex, tumor grade, treatment (primary, recurrence) |
| GSI 34 | 155 | primary, n= 101 recurrent, n=54 |
agea, boost volumea, dose, sex, treatment (primary, recurrence) a |
| HIBMC 7 | 23 | primary, n=23 | age, dose fractionation, ECOG PS, ion type, sexa, spacer placement, tumor volume |
| PSI 36 | 222 | primary, n=171 recurrent, n=51 |
age, compression of the brainstem or optic apparatusa, histologya, number of weekly fractions, sex, GTVa, treatment (primary, recurrence) |
| Present study | 21 | primary, n=8 recurrent, n=13 |
age, metal implantation, sex, treatment (primary, recurrence), dose, tumor volume |
a: factors significantly correlated with LC, PFS, or OS (p ≤0.05). HIT: Heidelberg Ion Beam Therapy Center; NIRS: National Institute of Radiological Sciences; GSI: Society for Heavy Ion Research in Darmstadt; HIBMC: Hyogo Ion Beam Medical Center; PSI: Center for Proton Therapy, Paul Scherrer Institute; GTV: gross tumor volume.