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. 2019 Jun 9;10(15):3389–3396. doi: 10.7150/jca.31676

Figure 4.

Figure 4

CCNC is a target of miR-15b in ccRCC. A) Reproduction of TCGA KIRC dataset of showed expression of genes significantly correlated with miR-15 expression with red color representing negative and green color representing positive correlation; B) Heat map showing expression of genes with negative correlation with miR-15b; C) Cross-referencing gene set in B) with miR-15b targets queried from TargetScanHuman revealing CCNC as potential target; D) Cartoon showing sequences match between miR-15b and CCNC with scramble and pmiR-15b lowering CCNC (Cyclin C) level in ccRCC cells.