Effects of Pae on CVF and PVCA. (A) For the comparison of CVF in different groups; (B) for the comparison of PVCA in different groups. *, P<0.05 vs. Veh group; #, P<0.05 vs. Iso group. Veh, vehicle; Iso, isoprenaline; Pae, paeoniflorin; Cap, captopril; CVF, collagen area/total area. PVCA, collagen area around the arterial lumen/arterial lumen area.