Effect of Pae on relative expression of TGF-β1 and Smad3 mRNA. (A) For the comparison of relative expression of TGF-β1 mRNA in different groups; (B) for the comparison of relative expression of Smad3 mRNA in different groups. *, P<0.05 vs. Veh group; #, P<0.05 vs. Iso group. Veh, vehicle; Iso, isoprenaline; Pae, paeoniflorin; Cap, captopril; TGF-β1, transforming growth factor β1.