Table 4.

Top 20 most frequent Terms in the dataset.

Rank	MeSH Terms	Freq.	Other Terms	Freq.	All Keywords	Freq. 1
1	biosensing techniques	32,646	biosensor(s)	2577	biosensing techniques	32,652
2	humans	18,333	surface plasmon resonance (spr)	667	humans	18,333
3	surface plasmon resonance	13,463	aptamer(s)	501	surface plasmon resonance (spr)	13,580
4	animals	11,540	gold nanoparticle(s)	476	animals	11,541
5	equipment design	7385	fluorescence	339	equipment design	7385
6	gold	5982	graphene	300	gold	5996
7	sensitivity and specificity	5539	sensor(s)	265	sensitivity and specificity	5539
8	electrodes	4937	immunosensor	247	electrochemistry	5051
9	electrochemistry	4907	nanoparticle(s)	234	electrodes	4941
10	equipment failure analysis	4653	electrochemical biosensor(s)	230	protein binding	4654
11	protein binding	4649	dna	220	equipment failure analysis	4653
12	reproducibility of results	4370	quantum dot(s)	200	reproducibility of results	4370
13	metal nanoparticles	4034	graphene oxide	194	metal nanoparticles	4040
14	kinetics	3913	microfluidic(s)	185	dna	3972
15	dna	3874	glucose	173	kinetics	3931
16	surface properties	3574	electrochemistry	166	surface properties	3574
17	electrochemical techniques	3494	biosensing	165	electrochemical techniques	3495
18	nanotechnology	3410	immunoassay(s)	162	nanotechnology	3468
19	limit of detection	3328	label-free	154	limit of detection	3341
20	mice	3023	aptasensor(s)	153	mice	3023

¹ It should be observed that since some of the terms (e.g., dna) appear in the same paper both as MeSH Terms and Other Terms, the frequency of their appearance in the All Keywords column would not be the sum of the frequency of their appearance in the other two terms. Some of the terms have been color-coded to facilitate comparison of their position in the list of MeSH terms and All Keywords.