Table 1.
Patient characteristics
|
Young (≤ 50 yr) |
Old (> 50 yr) |
P value | |
| (n = 45) | (n = 405) | ||
| Sex (male) | 39/45 (87%) | 342/405 (84%) | 0.86 |
| Ethnicity (white) | 43/44 (98%) | 377/387 (97%) | 0.70 |
| BMI, kg/m2 (mean ± SD) | 29.69 ± 6.05 | 28.53 ± 5.72 | 0.09 |
| BMI > 30 kg/m2 | 21/44 (48%) | 124/389 (32%) | 0.04 |
| Diabetes | 5/45 (11%) | 91/390 (23%) | 0.01 |
| Hypertension | 13/45 (29%) | 211/382 (55%) | < 0.001 |
| Family history of malignancy | 21/44 (48%) | 234/382 (61%) | 0.08 |
| Family history of esophageal adenocarcinoma | 1/44 (2%) | 17/382 (5%) | 0.78 |
| GERD symptoms | 24/44 (55%) | 148/386 (38%) | 0.04 |
| Smoking | |||
| Ever smoking | 25/44 (57%) | 297/393 (76%) | 0.01 |
| Current smoking | 4/44 (9%) | 47/392 (11%) | 0.75 |
| Pack-years (mean ± SD) | 13.97 ± 15.56 | 23.46 ± 27.21 | 0.02 |
| Alcohol | |||
| Ever alcohol | 37/45 (82%) | 297/387 (77%) | 0.52 |
| Current alcohol | 31/45 (69%) | 241/375 (64%) | 0.54 |
| Medication use | |||
| Proton pump inhibitors | 38/43 (88%) | 335/374 (90%) | 0.98 |
| Low-dose aspirin | 5/45 (11%) | 130/388 (34%) | < 0.01 |
| NSAIDs | 4/45 (9%) | 34/384 (9%) | 0.79 |
| Statins | 10/45 (22%) | 189/388 (49%) | < 0.001 |
| Endoscopy | |||
| Prague C, median (IQR), cm | 2 (0-5) | 1 (0-5) | 0.52 |
| Prague M, median (IQR), cm | 4 (2-7) | 4 (2-7) | 0.43 |
| Hiatus hernia | 35/45 (78%) | 350/405 (86%) | 0.12 |
BMI: Body mass index; GERD: Gastroesophageal reflux disease; NSAIDs: Nonsteroidal anti-inflammatory drugs; SD: Standard deviation; IQR: Interquartile range.