Table 1.
Antibiotic | MIC, mg/L | |
---|---|---|
CA-MHBa | 5% LB–RPMIb | |
Avibactam | 128 | 64 |
Ceftazidime | >64 | >64 |
Ceftazidime-avibactam (Avycaz) | 64 | 64 |
Meropenem | 128 | 512 |
Meropenem-vaborbactam (Vabomere) | 32 | 256 |
Tazobactam | >64 | >64 |
Ceftolozane-tazobactam | >64 | >64 |
Aztreonam | 512 | 32 |
LL-37 | 64 | 64 |
K. pneumoniae clinical isolate CDC 1100192, obtained from a sputum specimen, was used in this study.
aCation-adjusted Müller-Hinton broth (CA-MHB).
b5% Luria broth in Roswell Park Memorial Institute (RPMI) 1640 tissue culture medium.