Maximum percent change in prostate specific antigen (PSA) level from baseline during the main study for abiraterone acetate with prednisone, 5 mg, twice daily (n = 41), prednisone, 5 mg, once daily (n = 40), prednisone, 2.5 mg, twice daily (n = 38), or dexamethasone, 0.5 mg, once daily (n = 41). Dotted lines represent the PSA responders (50% reduction and 90% reduction in PSA). Prostate-specific antigen plots for prednisone, 5 mg, once daily, prednisone, 2.5 mg, twice daily, and dexamethasone, 0.5 mg, once daily exclude patients who were missing either baseline or postbaseline PSA values. Increases greater than 25% were cut off at 25%.