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. 2019 Jun 28;2(6):e196362. doi: 10.1001/jamanetworkopen.2019.6362

Table 2. Disease and Function Annotations From Ingenuity Pathway Analysis.

Categories Diseases or Functions Annotation Predicted Activation State Activation z Score Molecules, No. P Value P Value
>.01 <.01
Cell death and survival Cell death Decreased −3.117 77 .002 X
Cell death and survival Apoptosis Decreased −3.686 63 .001 X
Cell death and survival Necrosis Decreased −2.641 59 .04 X
Cell death and survival Cell death of tumor cell lines Decreased −3.029 50 .03 X
Cell death and survival Apoptosis of tumor cell lines Decreased −2.617 41 .02 X
Cell death and survival Cell viability Increased 5.026 38 .01 X
Cell death and survival Cell viability of tumor cell lines Increased 4.59 32 .02 X
Cell death and survival Cell viability of breast cancer cell lines Increased 3.094 10 .02 X
Cell death and survival Cell viability of blood cells Increased 2.195 6 .02 X
Cell death and survival Cell viability of leukocytes Increased 2.2 5 .03 X
Infectious diseases Viral Infection Increased 5.315 54 .002 X
Infectious diseases Infection by RNA virus Increased 4.494 31 .03 X
Infectious diseases Infection of cells Increased 4.594 29 .009 X
Infectious diseases Infection by HIV-1 Increased 4.301 23 .02 X
Infectious diseases Replication of RNA virus Increased 3.087 19 .004 X
Infectious diseases Infection of cervical cancer cell lines Increased 3.772 18 .01 X
Infectious diseases Replication of influenza A virus Increased 2.824 13 .005 X
Cell cycle, DNA replication, recombination, and repair Homologous recombination of cells Increased 2.828 8 <.001 X
Cellular development, cellular growth and proliferation Cell proliferation of breast cancer cell lines Increased 2.811 18 .03 X