Table 1. Characteristics of 638 856 Women Undergoing 1 693 163 Subsequent Digital Screening Mammograms Overall and by Invasive Breast Cancer and DCIS Status Within 1 Year of Follow-upa .
Characteristic | Screening Mammograms, % | ||
---|---|---|---|
No Invasive Cancer or DCIS (n = 1 685 648) | Invasive Cancer (n = 5326)b | DCIS (n = 2189)b | |
Age, y | |||
40-49 | 26.1 | 16.4 | 22.5 |
50-59 | 35.6 | 30.7 | 32.3 |
60-69 | 29.2 | 38.5 | 34.7 |
70-74 | 9.0 | 14.4 | 12.6 |
Race/ethnicity | |||
White, non-Hispanic | 67.0 | 73.3 | 66.2 |
Black, non-Hispanic | 7.5 | 7.1 | 6.8 |
Asian, Native Hawaiian, or Pacific Islander | 13.7 | 12.2 | 18.0 |
Hispanic | 4.8 | 3.1 | 3.4 |
Other, mixed, or unknown | 7.1 | 4.2 | 5.7 |
Menopausal status | |||
Premenopausal or perimenopausal | 29.8 | 20.7 | 26.2 |
Postmenopausal | |||
Current HT use | 7.3 | 9.9 | 7.7 |
No current HT use | 53.6 | 58.1 | 55.9 |
Current HT use unknown | 6.8 | 9.2 | 8.3 |
Surgical menopausal | 2.5 | 2.1 | 1.9 |
Family history of breast cancerc | 16.5 | 25.1 | 23.0 |
History of breast biopsy | 19.9 | 37.4 | 35.9 |
BI-RADS breast density | |||
Almost entirely fatty | 10.9 | 7.1 | 5.7 |
Scattered areas of fibroglandular densities | 42.1 | 41.3 | 38.6 |
Heterogeneously dense | 38.9 | 43.4 | 45.2 |
Extremely dense | 8.1 | 8.3 | 10.4 |
BI-RADS final assessment | |||
Normal (1) | 69.1 | 12.1 | 4.2 |
Normal, benign finding (2) | 28.2 | 7.4 | 2.6 |
Probably benign (3) | 1.7 | 4.2 | 5.5 |
Suspicious (4) | 1.0 | 56.4 | 83.6 |
Malignant (5) | 0 | 20.0 | 4.2 |
BCSC 5-y riskd | |||
0% to <1.00%, low | 29.6 | 14.1 | 18.2 |
1.00%-1.66%, average | 40.1 | 34.8 | 36.6 |
1.67%-2.49%, intermediate | 20.7 | 29.0 | 24.5 |
2.50%-3.99%, high | 8.4 | 18.2 | 17.2 |
≥4.00%, very high | 1.2 | 4.0 | 3.4 |
Abbreviations: BCSC, Breast Cancer Surveillance Consortium; BI-RADS, Breast Imaging Reporting and Data System; DCIS, ductal carcinoma in situ; HT, hormone therapy.
Subsequent screening examinations after recent prior mammogram within 9 to 30 months.
Invasive cancer cases and DCIS within 12 months of screening mammography.
Defined as first-degree relative (mother, sister, or daughter) with breast cancer.
The BCSC 5-year risk was calculated using age, race/ethnicity, first-degree family history of breast cancer, history of breast biopsy, and BI-RADS density.