Table 2. Baseline Demographic and Clinical Characteristics of Patients With Hyperthyroidism Treated With Radioactive Iodine.
| Baseline Characteristics | Tertile of Total Administered Activity, MBq | ||
|---|---|---|---|
| 1 (n = 6296) | 2 (n = 6248) | 3 (n = 6261) | |
| Total administered activity, mean (SD), MBqa | 160 (45) | 289 (46) | 724 (500) |
| No. of RAI treatments, mean (SD) | 1.3 (1.2) | 1.4 (0.9) | 2.4 (1.9) |
| Dose, mGy | |||
| Stomach | 65 (20) | 120 (25) | 320 (240) |
| Breastb | 60 (21) | 110 (29) | 280 (210) |
| Thyroid | 65 000 (31 000) | 110 000 (41 000) | 210 000 (160 000) |
| Study entry age, mean (SD), y | 47 (13) | 49 (14) | 52 (14) |
| Sex, No. (%) | |||
| Male | 1288 (20.5) | 1383 (22.1) | 1463 (23.4) |
| Female | 5008 (79.5) | 4865 (77.9) | 4798 (76.6) |
| Clinical impression, No. (%) | |||
| Suspect | 111 (1.8) | 96 (1.5) | 72 (1.2) |
| Mild | 1758 (27.9) | 1649 (26.4) | 1567 (25.0) |
| Moderate | 2564 (40.7) | 2605 (41.7) | 2639 (42.2) |
| Severe | 439 (7.0) | 596 (9.5) | 857 (13.7) |
| Unknown | 1424 (22.6) | 1301 (20.8) | 1126 (18.0) |
| Type of hyperthyroidism, No. (%) | |||
| Graves disease | 6127 (97.3) | 5967 (95.5) | 5521 (88.2) |
| Toxic nodular goiter | 115 (1.8) | 207 (3.3) | 612 (9.8) |
| Intermediate status | 54 (0.9) | 74 (1.2) | 128 (2.0) |
| Weight loss prior to surgical procedure, No. (%) | 4165 (66.2) | 3995 (63.9) | 3911 (62.5) |
| Amount of weight loss prior to surgical procedure, mean (SD), lb | 19 (13) | 21 (14) | 23 (16) |
| Medical history (prior to surgical procedure), No. (%) | |||
| Coronary heart disease | 257 (4.1) | 442 (7.1) | 654 (10.5) |
| Hypertensive heart disease | 364 (5.8) | 564 (9.0) | 720 (11.5) |
| Rheumatic heart disease | 137 (2.2) | 191 (3.1) | 222 (3.6) |
| Other heart disease | 274 (4.4) | 398 (6.4) | 718 (11.5) |
| Diabetes | 238 (3.8) | 303 (4.9) | 433 (6.9) |
| Treatment combinations, No. (%) | |||
| RAI only | 2589 (41.1) | 2597 (41.6) | 1996 (31.9) |
| RAI and surgical procedure | 278 (4.4) | 225 (3.6) | 191 (3.1) |
| RAI and drugs | 798 (12.5) | 726 (11.6) | 739 (11.8) |
| RAI, surgical procedure, and drugs | 2640 (41.9) | 2700 (43.2) | 3335 (53.3) |
Abbreviations: MBq, megabecquerel; RAI, radioactive iodine.
SI conversion factors: To convert pounds to kg, multiply by 0.45.
a
Includes diagnostic and therapeutic doses.
b
Women only.