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. 2019 May 23;44:86–97. doi: 10.1016/j.ebiom.2019.05.012

Fig. 1.

Fig. 1

Activation of pro-inflammatory and phagocytic cells is impaired in chronic inflammatory myopathy. (a) Schematic diagram of procedures for generating the acute muscle injury (AMI) and chronic inflammatory myopathy (CIM) models. (b) Representative CD11b, F4/80, and Ly6C counter plots for CIM and AMI (1, 2, and 5 days after injury). (c and d) Percentages of CD11b + F4/80+ macrophages (c), CD11b + F4/80 Ly6Clow anti-inflammatory macrophages (d), and CD11b + F4/80 Ly6Chi pro-inflammatory macrophages (d). (e) Representative CD11b and CD49b counter plot in CIM and AMI (1, 2, and 5 days after injury). (f) Percentage of CD11b + CD49b NK cells. Quantitative data are shown as means ± SEM with dot plots. P-values were determined by one-way ANOVA adjusted by Tukey's method. (*P < .05, **P < .001).