Table 3.

Sensitivity and specificity of phenotypic ASTs and genotypic AMR predictions against the broth microdilution reference AST. Clinical breakpoints are applied as interpretive criteria for all ASTs

Antimicrobial	Sensitivity (95% CI)			Specificity (95% CI)
	Disk diffusion	Agar dilution	Genotyping	Disk diffusion	Agar dilution	Genotyping
Ampicillin	0.95 (0.85–0.99)	0.95 (0.85–0.99)	0.96 (0.88–1)	1 (0.92–1)	1 (0.92–1)	0.93 (0.82–0.99)
Chloramphenicol	0.92 (0.8–0.98)	0.71 (0.57–0.83)	0.94 (0.83–0.99)	0.98 (0.9–1)	0.98 (0.9–1)	0.94 (0.84–0.99)
Gentamicin	0.71 (0.29–0.96)	0.86 (0.42–1)	0 (0–0.41)	1 (0.96–1)	1 (0.96–1)	1 (0.96–1)
Nalidixic Acid	0.82 (0.63–0.94)	0.75 (0.55–0.89)	0.82 (0.63–0.94)	1 (0.95–1)	0.96 (0.89–0.99)	1 (0.95–1)
Sulfamethoxazole	0.97 (0.9–1)	0.97 (0.9–1)	0.67 (0.54–0.78)	1 (0.89–1)	0.94 (0.8–0.99)	0.97 (0.84–1)
Streptomycin	0.96 (0.8–1)	0.38 (0.2–0.59)	0.92 (0.75–0.99)	0.59 (0.47–0.7)	1 (0.95–1)	0.43 (0.32–0.55)
Trimethoprim-Sulfamethoxazole	1 (0.88–1)	0.93 (0.78–0.99)	0.97 (0.83–1)	1 (0.95–1)	0.97 (0.9–1)	0.96 (0.88–0.99)
Overall	0.94 (0.9–0.96)	0.83 (0.78–0.87)	0.84 (0.79–0.88)	0.93 (0.9–0.95)	0.98 (0.97–0.99)	0.88 (0.85–0.91)