Table 1.
Characteristics of the study population at baseline
| CVA with low FEF50% (n = 27) | CVA with normal FEF50% (n = 30) | p value | |
|---|---|---|---|
| Age (years) | 43.2 ± 14.1 | 41.1 ± 15.6 | 0.33 |
| Gender (male: female) | 56%/44% | 27%/73% | 0.48 |
| Medical history | |||
| Daytime cough | 11 (40.7%) | 6 (20%) | 0.33 |
| Nighttime cough | 19 (70.4%) | 23 (77.6%) | 0.68 |
| Cough affects sleep | 19 (70.4%) | 15 (50.0%) | 0.57 |
| Chest tightness | 20 (74.1%) | 10 (33.3%) | 0.40 |
| Allergic rhinitis | 17 (62.9%) | 22 (73.3%) | 0.15 |
| Allergic family history | 15 (55.6%) | 15 (50.0%) | 0.27 |
| Pulmonary function test | |||
| FEV1/FVC (%) | 77.4 ± 6.06 | 86.0 ± 6.12 | < 0.001 |
| FEV1% | 90.77 ± 11.4 | 99.8 ± 13.6 | 0.97 |
| FEF50% | 62.95 ± 8.06 | 85.7 ± 16.7 | < 0.001 |
| Asthma control assessments | |||
| ACT | 17.9 ± 4.4 | 18.3 ± 3.0 | 0.57 |
| ACQ | 1.79 ± 0.99 | 1.43 ± 0.66 | 0.14 |
| Induced sputum | |||
| Total number of cells (105/mL) | 5.6 ± 1.2 | 6.7 ± 0.9 | 0.45 |
| Neutrophils (%) | 30.5 ± 6.2 | 47.2 ± 10.9 | 0.67 |
| Eosinophils (%) | 3.6 ± 0.2 | 2.7 ± 0.4 | 0.55 |
| Lymphocytes (%) | 7.8 ± 0.6 | 9.2 ± 0.2 | 0.23 |
| Macrophages (%) | 36.4 ± 4.2 | 32.3 ± 3.3 | 0.78 |