Table 1.
Common risk genes identified in genetic meta-analysis of Alzheimer's disease and in the study of metabolic traits associated with mitochondrial and nuclear mitochondrial variants and genes [38].
| Gene SNV | Full gene name | SNV |
|---|---|---|
| WWOX | WW domain-containing oxidoreductase | rs1847591 |
| MTCH2 | Mitochondrial carrier 2 | rs4752856 |
| PSMC3 | Proteasome 26S subunit, ATPase 3 | Expression regulated by MTCH2 rs4752856 |
| C1QTNF4 | C1q and TNF-related 4 | Expression regulated by MTCH2 rs3817335 |
| CELF1 | CUGBP Elav-like family member 1 | Expression regulated by MTCH2 rs7118178 |
| ACP2 | Acid phosphatase 2, lysosomal | Expression regulated by NR1H3 rs7120118 |