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. 2019 Jul 2;17:182. doi: 10.1186/s12967-019-1911-6

Table 2.

Spearman’s correlation coefficients (r) of clinical TNM stage, Ki 67 and with combined IVIM and non-Gaussian diffusion parameters

ADC Dt f D* MK MD
cTNM Ki67 cTNM Ki67 cTNM Ki67 cTNM Ki67 cTNM Ki67 cTNM Ki67
50th − 0.61 − 0.23* − 0.04 − 0.11 0.04 0.22* − 0.14 − 0.06 0.02 0.14 − 0.05 − 0.60
5th − 0.23 − 0.14 − 0.02 − 0.08 0.04 0.13 − 0.04 0.01 0.05 0.18* − 0.02 − 0.13
95th − 0.40 − 0.24* − 0.07 − 0.21* 0.04 0.20* − 0.12 − 0.01 0.03 0.07 − 0.10 − 0.05
Skewness 0.28* 0.11 0.12 0.16 − 0.02 − 0.20* 0.05 − 0.01 − 0.12 − 0.07 0.16 − 0.04
Kurtosis 0.21* 0.19* 0.04 0.09 − 0.01 − 0.25* 0.09 − 0.02 − 0.12 − 0.13 0.06 − 0.01
Contrast − 0.13 − 0.12 − 0.12 − 0.03 − 0.02 0.23* − 0.10 − 0.02 0.01 0.12 − 0.01 0.12
Entropy − 0.14 − 0.13 − 0.01 − 0.04 0.113 0.06 − 0.02 0.21 0.024 0.11 0.05 − 0.12

ADC apparent diffusion coefficient, Dt true diffusion coefficient, f perfusion fraction diffusion, D* pseudo-diffusion coefficient, MK mean kurtosis, MD mean diffusivity

*p < 0.05 was considered statistically significant