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. 2019 Jun 17;2019:7604396. doi: 10.1155/2019/7604396

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Copyright © 2019 Yujin Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Signs of iris stromal atrophy in KR/sFRP1 mice. Overall surface texture of irises for control (a) and KR/sFRP1 (b) mice. High-magnification images revealed the difference between the two (c, d). In the control eyes, the surface area between vessels was smooth and uniform. In the KR/sFRP1 eyes, the blood vessels were bulging and tortuous. Iris angiography images of the control (e) and KR/sFRP1 (f) mice further demonstrate tortuous vessels. The atrophic findings of the KR/sFRP1 irises further demonstrate ocular findings consistent with aging.