Table 1.
Patient demographics by category.
Category Variables | Total | Normal | High | p Value |
---|---|---|---|---|
Number of cases | 205 | 154 | 51 | NA |
Gender: Female | 46.3% | 48.1% | 41.2% | 0.394 |
Gender: Male | 53.7% | 51.9% | 58.8% | |
AHD ≥ 2 Mo: Yes | 31.2% | 31.2% | 31.4% | 0.95 |
Prior Malignancy: Yes | 16.6% | 14.9% | 21.6% | 0.3 |
Prior Chemo: Yes | 8.8% | 7.8% | 11.8% | 0.41 |
Prior XRT: Yes | 8.3% | 5.8% | 15.7% | 0.027 |
Infection: Yes | 27.8% | 26.0% | 33.3% | 0.35 |
WHO Class: Not in other | 60.5% | 60.4% | 60.8% | 0.72 |
WHO class: Multilineage Dysp | 15.6% | 14.3% | 19.6% | |
WHO Class: therapy related | 8.3% | 9.1% | 5.9% | |
WHO Class: AML w Char Gene Abnormality | 15.6% | 16.2% | 13.7% | |
FAB: 0 | 5.9% | 7.1% | 2.0% | < 0.0001 |
FAB: 1 | 12.7% | 16.2% | 2.0% | |
FAB: 2 | 33.2% | 39.6% | 13.7% | |
FAB: 4 | 28.3% | 24.0% | 41.2% | |
FAB: 5 | 12.2% | 6.5% | 29.4% | |
FAB: 6 | 2.0% | 1.3% | 3.9% | |
FAB: 7 | 2.4% | 2.6% | 2.0% | |
FAB: 8 | 2.9% | 2.6% | 3.9% | |
FAB: 10 | 0.5% | 0.0% | 2.0% | |
Cytogenetics: Favorable | 10.7% | 13.6% | 2.0% | 0.06 |
Cytogenetics: Intermediate | 46.3% | 45.5% | 49.0% | |
Cytogenetics: Unfavorable | 42.9% | 40.9% | 49.0% | |
Response: CR | 57.6% | 55.8% | 62.7% | 0.31 for CR + PR vs resistant and excluding Fail |
Response: PR | 2.4% | 3.2% | 0.0% | |
Response: Resistant | 30.2% | 32.5% | 23.5% | |
Response: Fail | 9.8% | 8.4% | 13.7% | |
Alive | 19.0% | 21.4% | 11.8% | 0.11 |
Relapse: No | 42.4% | 48.8% | 25.0% | 0.036 |
Relapse: Yes | 61.9% | 57.0% | 75.0% |