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. 2019 Jul 2;12:40. doi: 10.1186/s13072-019-0285-6

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Genes exhibiting up-regulated expression in the 701Ri-1-5 mutant have decreased H3K4me2 levels. a–d Average density plots presenting the H3K4me1/H3K4me2/H3K4me3 and H3K36me3 distribution patterns along genes exhibiting significantly up-regulated expression (up: 1572 genes with expression levels > 1.5-fold higher in the 701Ri-1-5 mutant than in the wild-type NIP), down-regulated expression (down: 1508 genes with expression levels > 1.5-fold lower in the 701Ri-1-5 mutant than in the wild-type NIP), and no significant changes (Invariant) in the NIP (solid line) and 701Ri-1-5 mutant (dashed line) samples. The plots were generated from 1 kb upstream of the TSS to 1 kb downstream of the TTS