Table 4.
Univariate analysis of prognostic factors related to local progression-free survival rate, distant progression-free survival rate and overall survival rate
| Parameters | No. of patients | 5-year local progression-free survival rate (%) | 5-year distant progression-free survival rate (%) | 5-year overall survival rate (%) |
|---|---|---|---|---|
| Age at time of recurrence | ||||
| ≤50 years | 30 | 50.8 ± 11.3 | 29.1 ± 8.6 | 43.3 ± 10.5 |
| >50 years | 21 | 56.8 ± 11.8 | 48.7 ± 11.8 | 49.9 ± 12.3 |
| P value | 0.995 | 0.476 | 0.912 | |
| Disease-free interval | ||||
| ≤2 year | 27 | 34.8 ± 11.6 | 18.7 ± 8.0 | 25.3 ± 10.0 |
| > 2 year | 24 | 73.2 ± 10.5 | 57.5 ± 10.9 | 69.4 ± 10.7 |
| P value | 0.014 | 0.007 | 0.003 | |
| No. of recurrence | ||||
| Single | 25 | 80.0 ± 8.0 | 58.8 ± 10.1 | 73.2 ± 9.5 |
| Multiple and diffused | 26 | 18.2 ± 10.6 | 10.7 ± 7.0 | 14.5 ± 8.9 |
| P value | 0.003 | 0.001 | 0.001 | |
| Size of largest recurrence | ||||
| < 3 cm | 32 | 52.1 ± 10.7 | 31.0 ± 8.8 | 40.6 ± 10.3 |
| ≥3 cm | 19 | 55.8 ± 13.0 | 46.2 ± 11.8 | 53.9 ± 12.2 |
| P value | 0.819 | 0.769 | 0.885 | |
| Systemic treatment after concurrent CRT | ||||
| Yes | 46 | 59.8 ± 9.1 | 38.0 ± 8.0 | 48.5 ± 8.9 |
| No | 9 | 29.6 ± 16.4 | 29.6 ± 16.4 | 33.9 ± 18.2 |
| P value | 0.080 | 0.453 | 0.378 | |
| Tumor response | ||||
| CR | 36 | 60.4 ± 9.4 | 38.6 ± 8.5 | 52.9 ± 9.6 |
| PR/SD/PD | 15 | 33.6 ± 15.3 | 30.2 ± 13.6 | 27.9 ± 13.3 |
| P value | 0.054 | 0.799 | 0.047 | |