Table 3.

GO molecular function terms enriched with a significant number of genes involved in CP

GO molecular function	CP genes in molecular function category
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity	FGF19, FGFR2, FGF18, FGFR1, FGF8, FGF7, FGFR3, FGF9, ERBB2, PDGFRA, FGF10, FGF1, FGF2, FGF3, FGF4
GO:0016303 1-phosphatidylinositol-3-kinase activity	FGF19, FGFR2, FGF18, FGFR1, FGF8, FGF7, FGFR3, FGF9, FGF10, FGF1, FGF2, FGF3, FGF4
GO:0008083 growth factor activity	BMP4, FGF19, FGF18, BMP2, FGF8, FGF7, FGF9, GDF6, JAG2, TGFB3, FGF10, TGFB1, TGFA, FGF1, BMP7, FGF2, FGF3, FGF4
GO:0005088 Ras guanyl-nucleotide exchange factor activity	FGF19, FGFR2, FGF18, FGFR1, FGF8, FGF7, FGFR3, FGF9, ERBB2, PDGFRA, FGF10, FGF1, FGF2, FGF3, FGF4
GO:0005104 fibroblast growth factor receptor binding	FGF19, FGF8, FGF7, FGF9, FGF10, FGF1, FGF2, FGF3, FGF4
GO:0004713 protein tyrosine kinase activity	FGFR2, FGF18, FGFR1, FGF8, FGF7, FGFR3, FGF9, RYK, ERBB2, FGF10, FGF1, FGF2, FGF3, FGF4
GO:0008201 heparin binding	FGFR2, BMP4, FGFR1, FGF7, CRISPLD2, FGF9, FGF10, PTCH1, FGF1, BMP7, FGF2, FGF4
GO:0005109 frizzled binding	WNT5A, DVL3, WNT10A, RYK, WNT3A, ROR2, WNT11
GO:0042803 protein homodimerization activity	FGFR2, FGFR1, NOG, GDF6, SLC6A4, NECTIN1, NECTIN2, TBX1, MYH9, MID1, TGFB1, GCH1, UGT1A7, STOM, PDGFRA, TFAP2A, PCYT1A, CBS