Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 1;38:283. doi: 10.1186/s13046-019-1279-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — High expression of MUC17 is associated with improved prognosis in GC patient and inflammatory cytokines induce the expression of MUC17 in GC cells. a Higher MUC17 expression was detected in GC tissues compared to normal tissues using information from the TCGA_GC database. The median was shown. b Higher levels of MUC17 expression associated with improved prognosis in patients using information from the TCGA_GC database. c The expression of MUC17 in GC tissues and adjacent normal tissues detected by immunohistochemistry. Scale bar, 50 μM. d High levels of MUC17 expression associated with favourable prognoses in our study cohort. e Co-expression of MUC17 with IL1β and IL8 in GC tissues detected by immunohistochemistry. Scale bar, 50 μM. f Analysis the expression association between MUC17 and IL1β (left) and IL8 (right) by using TCGA_GC transcriptional database. g Treatment with IL1β (left) and IL8 (right) increased the expression of MUC17 determined by RT-PCR. h Treatment with IL1β and IL8 increased the expression of MUC17 determined by qPCR. Error bars represent ± SD of three experiments (*, P < 0.05). i Upper, scheme of MUC17 promoter-luciferase fusion plasmids. Lower, treatment with IL1β and IL8 increased the activity of the MUC17 promoter measured by luciferase assays. Error bars represent ± SD of three experiments (*, P < 0.05)