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. Author manuscript; available in PMC: 2019 Jul 2.
Published in final edited form as: J Chromatogr A. 2017 Nov 24;1531:83–103. doi: 10.1016/j.chroma.2017.11.027

Table 2.

Hildebrand solubility parameters, MPa0.5, calculated using Eq. (1) and values listed in Table 1 for the mixtures of solvents used as mobile phase.

Solvent j % of solvent in THF mobile phase
10 20 30 40 50 60 70 80 90 100

Hildebrand Solubility, MPa0.5
Tetrahydrofuran 18.6
Chloroform 18.6 18.6 18.7 18.7 18.7 18.7 18.7 18.8 18.8 18.8
Acetone 18.7 18.7 18.9 19.0 19.1 19.2 19.3 19.4
2-Propanol 19.1 19.5 20.0 20.5
Dimethylformamide 19.2 19.7 20.3 20.8 21.4 21.9 22.5
Ethanol 19.2 19.8 20.4 21.0
Acetonitrile 19.2 19.8 20.5 21.1
Methanol 19.7 20.8 21.9 23.0