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. 2019 Jun 25;9:217. doi: 10.3389/fcimb.2019.00217

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Copyright © 2019 Afrin, Murase, Kounosu, Hunt, Bligh, Maeda, Hino, Maruyama, Tsai and Kikuchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative abundances of the operational taxonomic units (OTUs) that significantly changed during the infection period. Six genera were found to have significantly changed in abundance at 8–11 days post-infection (DPI) relative to the control: Bacteroides (Bacteroidetes), Prevotella (Bacteroidetes), S24-7 (Bacteroidetes), an unclassified genus derived from Rikenellaceae (Bacteroidetes), Prevotellaceae (Bacteroidetes), and Candidatus Arthromitus (Firmicutes). Solid and break lines represent the naïve control mice (n = 3) and the infected mice (n = 3), respectively.