Table 1.

Nuclear Mutation Rates

Substitution	N	μ
GC -> AT	80	4.82E-10
AT -> GC	38	2.18E-10
GC -> CG	24	1.44E-10
AT -> TA	4	2.30E-11
Intergenic	57	3.88E-10
Genic		5.00E-10
Intron	5
Nonsyn	57
Syn	26
UTR	3
Frame shift	1
Codon insertion	2

N, number of de novo mutations; μ, mutation rate per site per generation.