Table 1.
Comparison of baseline characteristics according to the presence of sarcopenia
| Variable | Total (n=5,989) | Control (n=5,674) | Sarcopenia (n=315) | P |
|---|---|---|---|---|
| Age (yr) | 53.2±9.4 | 53.0±9.2 | 57.1±11.4 | <0.001 |
|
| ||||
| Male sex | 3,431 (57.3) | 3,201 (56.4) | 230 (73.0) | <0.001 |
|
| ||||
| Height (cm) | 165.7±8.2 | 165.8±8.2 | 163.7±8.4 | <0.001 |
|
| ||||
| Weight (kg) | 64.7±11.7 | 64.1±11.2 | 75.0±14.5 | <0.001 |
|
| ||||
| BMI (kg/m2) | 23.4±3.0 | 23.2±2.8 | 27.8±3.6 | <0.001 |
|
| ||||
| WC (cm) | ||||
| Male | 88.0±7.3 | 87.4±6.7 | 97.3±8.4 | <0.001 |
| Female | 79.7±7.8 | 79.2±7.3 | 92.8±10.0 | <0.001 |
|
| ||||
| VFA (cm2) | 114.4±55.4 | 110.9±53.0 | 179.3±57.7 | <0.001 |
|
| ||||
| ASM (kg) | 19.8±4.6 | 19.8±4.5 | 19.8±4.9 | 0.993 |
|
| ||||
| ASM% | 30.4±3.5 | 30.7±3.3 | 26.2±3.1 | <0.001 |
|
| ||||
| SBP (mmHg) | 116.4±13.7 | 116.0±13.6 | 124.1±14.2 | <0.001 |
|
| ||||
| DBP (mmHg) | 74.3±10.4 | 74.1±10.3 | 78.2±10.8 | <0.001 |
|
| ||||
| AST (IU/L) | 25.3±29.6 | 25.1±30.3 | 28.8±13.4 | 0.034 |
|
| ||||
| ALT (IU/L) | 26.3±34.8 | 25.8±35.3 | 35.9±23.5 | <0.001 |
|
| ||||
| GGT (IU/L) | 35.2±39.1 | 34.5±38.7 | 48.1±42.7 | <0.001 |
|
| ||||
| Cholesterol (mg/dL) | 194.7±35.1 | 194.6±35.3 | 196.5±37.7 | 0.352 |
|
| ||||
| TG (mg/dL) | 107.6±79.9 | 106.5±80.6 | 128.6±62.2 | <0.001 |
|
| ||||
| HDL cholesterol (mg/dL) | ||||
| Male | 48.0±9.8 | 48.1±9.8 | 46.4±8.9 | 0.010 |
| Female | 56.0±11.4 | 56.0±11.4 | 54.9±9.7 | 0.307 |
|
| ||||
| LDL cholesterol (mg/dL) | 121.9±30.7 | 121.6±30.5 | 127.4±33.6 | 0.004 |
|
| ||||
| Fasting glucose (mg/dL) | 97.6±19.7 | 97.1±19.1 | 106.3±27.4 | <0.001 |
|
| ||||
| HbA1c (%) | 5.7±0.6 | 5.7±0.6 | 6.0±0.8 | <0.001 |
|
| ||||
| Uric acid (mg/dL) | 5.5±1.4 | 5.4±1.4 | 6.2±1.6 | <0.001 |
|
| ||||
| Diabetes mellitus | 299 (5.0) | 272 (4.8) | 27 (8.6) | 0.004 |
|
| ||||
| Hypertension | 892 (14.9) | 804 (14.2) | 88 (27.9) | <0.001 |
|
| ||||
| Smoking | <0.050 | |||
| Never | 1,540 (46.5) | 1,489 (47.1) | 51 (34.0) | |
| Former | 1,137 (34.3) | 1,068 (33.8) | 69 (46.0) | |
| Current | 635 (19.2) | 605 (19.1) | 30 (20.0) | |
|
| ||||
| NAFLD | 2,290 (38.2) | 2,071 (36.5) | 219 (69.5) | <0.001 |
Values are presented as mean±standard deviation or number (%).
BMI, body mass index; WC, waist circumference; VFA, visceral fat area; ASM, appendicular skeletal muscle mass; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyltransferase; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HbA1c, glycosylated hemoglobin; NAFLD, nonalcoholic fatty liver disease.