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. 2019 Jun 25;13:672. doi: 10.3389/fnins.2019.00672

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Copyright © 2019 Zhou, Li, Yang and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PhNR of normal and glaucomatous rat eyes. (A,B) Representative traces of the “a” wave, the “b” wave, and PhNR in a control eye (A) and a glaucomatous eye (B) in step 3 with the stimulus applied at 22.76 cd.s/m²–0.33 Hz. (C,D) Representative waves in a PBS-treated glaucomatous eye (C) and quercetin-treated glaucomatous eye (D) in the same step and with the same stimulus used in (A,B). (E) Quantitative analysis of PhNR amplitude (n = 12). The amplitude was normalized to the amplitude in control retinas. ^∗∗p < 0.01 (one-way analysis of variance). a, “a” wave; b, “b” wave; PhNR, photopic negative response.