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. 2019 Jun 25;13:672. doi: 10.3389/fnins.2019.00672

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Copyright © 2019 Zhou, Li, Yang and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quercetin significantly inhibited the frequency, but not the amplitude, of mEPSCs in OFF-type RGCs. (A) Representative traces showing the effect of 10 μM quercetin on glutamatergic mEPSCs in OFF-type RGCs. (A1) Control conditions; (A2) during quercetin treatment; (A3) recovery. Vertical bar, 5 pA; horizontal bar, 2 s. (B) Summarized data from 14 OFF-type RGCs showing that 10 μM quercetin significantly decreased the average frequency of glutamatergic mEPSCs. (C) Summarized data from 14 OFF-type RGCs showing that 10 μM quercetin did not change the average amplitude of glutamatergic mEPSCs. ^∗∗p < 0.01, paired Student’s t-test.