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. 2017 Apr 14;3(2):248–266. doi: 10.3934/microbiol.2017.2.248

Table 1. Production characteristics of rDen 1 DIII protein using modified SB medium in E. coli.

Cultivation mode Dry cell weight (g/l) Total protein concentration (g/l) Final product concentration (mg/l) Specific product yield (mg/g)
Shake flask 2.56 0.657 16 6.26
Batch fermentationa 5.0 1.34 62 12.40
Fed-batch fermentationb 16.0 3.38 161 10.06

aAt 5 liter scale; bAt 10 liter scale.