Table I.
Comparison of haematological values for HbS-HPFH types 1 or 2.
| HPFH 1 (n = 7, 2 males) |
HPFH 2 (n = 23, 10 males) |
t-test P-value* | |||
|---|---|---|---|---|---|
| Mean (SD) | Range | Mean (SD) | Range | ||
| Average HbF (%) | 32⋅6 (3⋅0) | 28⋅7–36⋅0 | 31⋅0 (2⋅3) | 27⋅1–35⋅2 | 0⋅26 |
| Haemoglobin (g/l) | 130 (8⋅0) | 119–149 | 125 (12) | 100–148 | 0⋅07 |
| MCV (fl) | 73⋅7 (6⋅2) | 65⋅0–93⋅6 | 74⋅9 (6⋅4) | 65⋅0–99⋅2 | 0⋅48 |
HPFH, Hereditary persistence of fetal haemoglobin; HbS-HPFH, compound heterozygotes for HbS and HPFH; MCV, mean corpuscular volume; SD, standard deviation.
There was no significant difference between the average HbF (in patients ≥5 years old), haemoglobin, or MCV between these groups based on t-test analysis.