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. 2015 Jul 22;35(29):10600–10612. doi: 10.1523/JNEUROSCI.3238-14.2015

Figure 4.

Figure 4.

Maturation of connections with inhibitory neurons. A, Representative images of LMTs associated with developmentally and adult-generated DGCs (2, 4, 6, and 8 weeks after infection). Scale bar, 5 μm. B, Three-dimensional reconstructions of LMTs (orange) show the emergence of multiple filopodia (blue) from their surface. Four-week-old LMTs show the highest number of filopodia. Scale bar, 5 μm. C, The number of filopodia/LMTs varies as a function of post-infection delay. Inset, Number of filopodia normalized with respect to LMT density. D, Filopodia head size varies as a function of post-infection delay. Inset, Filopodia length does not change as a function of post-infection delay. E, En passant density in CA3 varies as a function of post-infection delay. F, En passant area in CA3 varies as a function of post-infection delay. G, En passant density in the hilus as a function of post-infection delay. H, En passant area in hilus does not change as a function of post-infection delay.