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. 2015 Aug 19;35(33):11623–11633. doi: 10.1523/JNEUROSCI.1386-15.2015

Figure 3.

Figure 3.

LiCl after conditioning induces CTA and inhibitory avoidance amnesia that is reversible with exposure to a reminder or LiCl. A, Timeline of experiment. After sucrose (S) exposure, groups of rats (n = 9–11; see B) received one injection of LiCl (0.25 m; 300 mg/kg) or Sal just after conditioning and another injection of Sal or LiCl (0.15 m; 127 mg/kg) 30 min before the retention test. Another group that received an LiCl injection after conditioning and was exposed to the reminder, 5 min before testing. B, Experiment 5, Mean ± SEM response latency obtained during the test, 48 h after inhibitory avoidance conditioning or pseudoconditioning. ***p < 0.001 versus Sal; ++p < 0.01 versus LiCl. C, Experiment 5, Values displayed as mean ± SEM amount of sucrose intake obtained during the CTA occurring 48 h after exposure to the sucrose solution and the inhibitory avoidance conditioning test or pseudoconditioning. ***p < 0.001 versus Sal; ++p < 0.05 versus LiCl; #p < 0.05 versus LiCl60. D, Experiment 5, Mean ± SEM weight obtained in nondeprived rats receiving an injection of Sal or Cyclo, 1 week after testing (white bars) and the following day (black bars). **p < 0.01 versus Sal.