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. 2019 Jul;79:267–273. doi: 10.1016/j.bbi.2019.02.011

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 1 — All AD-RPS (SNPs across whole genome) regressed on hippocampal volume (across whole genome; red) and microglia AD-RPS (SNPs within 56 microglia-mediated immunity genes (Sims et al., 2017; blue)). Left Y-axis = R²; Right Y axis = beta coefficients (+/− 95% confidence), X-axis = P-Threshold of AD-RPS. All AD-RPS are performed after the removal of the APOE and MHC loci. P values are annotated above each bar that denotes variance explained (R²) at each AD-RPS/P – threshold.