Figure 8.

A, Pleiotrophin transiently expressed in the corpus callosum by the cuprizone treatment. Images show the dorsal corpus callosum. Brain sections from wild-type (+/+) and Ptprz-deficient (−/−) mice were stained with anti-PTN. Mice were fed a cuprizone-containing diet and then returned to a normal diet. Scale bars, 25 μm. B, Scatterplot showing the number of anti-PTN-stained puncta in the corpus callosum. Open circles, Wild-type mouse; closed circles, Ptprz-deficient mouse. n = 10 for each group. No genotypic differences were detected by two-way ANOVA.