Table 1.
LL (n = 17) | SS (n = 15) | p for difference | |
---|---|---|---|
Genetics | |||
5-HTTLPR | Homozygous long | Homozygous short | |
rs25531 | A/A | ||
rs25532 | C/C | ||
Demographics | |||
Gender (females/males) | 12/5 | 10/5 | |
Age | 23.8 ± 0.5 | 23.9 ± 0.9 | 0.920 |
Weight | 67.8 ± 2.1 | 65.7 ± 0.7 | 0.518 |
Verbal IQ | 105.8 ± 10.1 | 110.8 ± 9.0 | 0.154 |
Questionnaires | |||
BDI-II | 2.85 ± 0.7 | 4.03 ± 0.8 | 0.300 |
EPQ-RS neuroticism | 2.94 ± 0.61 | 4.73 ± 0.67 | 0.056 |
EPQ-RS psychoticism | 2.59 ± 0.33 | 3.2 ± 0.47 | 0.288 |
EPQ-RS extraversion | 9.24 ± 0.71 | 8.07 ± 0.87 | 0.302 |
EPQ-RS lie scale | 2.76 ± 0.50 | 0.4 ± 0.13 | < 0.001 |
BIS-11 total | 62.3 ± 2.2 | 65.4 ± 2.1 | 0.306 |
BIS attentional | 15.6 ± 0.6 | 16.4 ± 0.7 | 0.410 |
BIS motor | 23.5 ± 0.8 | 24.1 ± 0.7 | 0.544 |
BIS nonplanning | 23.2 ± 1.4 | 25.5 ± 1 | 0.187 |
Group LL included only the high expressing homozygous LAC genotype; group SS included C and T variants at rs25532. Groups did not differ with regard to demographics, IQ, and baseline depression scores. A significant difference was observed on the lie scale of the EPQ-RS, indicating higher scores of social desirability in the LL group. Additionally, a trend toward higher neuroticism scores was seen in group SS, which is in accordance with previous studies (Schinka et al., 2004). Impulsiveness measured with the BIS-11 did not show group differences. Values represent mean ± SE. BDI, Beck Depression Inventory; EPQ-RS, Eysenck Personality Questionnaire Revised Short Scale; BIS-11, Barratt Impulsiveness Scale.