Figure 2.

TBSS analysis of DTI measures across the whole brain. Red-yellow shows clusters where RIS subjects (A) and RRMS patients (B) had DTI abnormalities (lower FA or higher AD and RD; p < 0.01, corrected) with respect to NC. C, Regions of WM tracts where RIS subjects had lower AD and RD than RRMS patients are shown (p < 0.05, corrected). Green is the mean WM skeleton. Background image, shown in radiological convention, is the FMRIB58 FA standard space. See Results and Table 2 for details. See text for abbreviations.