Figure 1.

Cortical cooling in acute and chronic experiments. A, Drawing shows the shape and position of cooling duralumin plates in acute (left, the plate shown with gray) and chronic (right) experiments. B, Calibration of the cooling plate. The black and red curves show the temperature of the plate and the cortex, respectively. C, The average cortical temperature (red curve) and the surface temperature (blue curve) plotted against the cooling plate temperature. The temperatures used in control, during cooling and heating, are shown with gray (see Materials and Methods).