Skip to main content
. 2015 Dec 2;35(48):15934–15947. doi: 10.1523/JNEUROSCI.1924-15.2015

Figure 5.

Figure 5.

Intraganglionic injection of CCL2 neutralizing antibodies abolishes conditioning effects. A, Representative images of Iba1 staining in L5 DRGs obtained 7 d after SNI of animals with intraganglionic injection of IgG or CCL2-neutralizing antibody (αCCL2). The injection was performed immediately after SNI. Scale bars, 50 μm. B, Comparison of the number of macrophages. N = 3 animals per group. ***p < 0.001. C, Representative images of neurons cultured from L5 DRGs with intraganglionic injection of IgG or αCCL2 of animals subjected 7 d previously to SNI. Scale bars, 100 μm. D, Quantification of neurite outgrowth. N = 3 animals per group. ***p < 0.001.