Figure 1.

Experimental paradigm and recording technique. A, Schematic of representative pro- and anti-saccade trials. Animals were required to perform correct responses toward (pro-saccade) or away from (anti-saccade) a peripheral stimulus to receive liquid reward. Dashed circles represent gaze of the animal. Arrows indicate direction of saccade. Each trial is followed by a 1700–2200 ms ITI. B, Single-unit extracellular recordings were performed in macaque DLPFC using glass iontophoretic electrodes. Beige area represents recording locus. Muscarinic antagonist scopolamine (represented in blue) is shown. AC, Arcuate sulcus; PS, principal sulcus.