Figure 6.

Absence of NSC-derived astroglial production in the forebrain gray matter and the spinal cord in normal adults. A–D, Low-magnification images of coronal brain sections at 270 d post-TM. EYFP⁺/GFAP⁺ cells migrated into the corpus callosum in both close proximity to the SVZ (A, B) and distal to the SVZ (C, D), but did not enter the striatum (A, B) or cortex (C, D). E, The absence of EYFP⁺ cells outside the central cannel at 270 d post-TM. F, Higher-magnification image of the area outlined by a rectangle in E, showing the lack of NSC-derived astrogliogenesis in the adult spinal cord. CC, Corpus callosum; CTX, cortex; LV, lateral ventricle; SP, spinal cord; ST, striatum. Scale bars, 100 μm.