Table 3. RMST at 10 years for biochemical failure determined by using of curves Kaplan–Meier and FP survival model, on 249 men treated by RP for prostate cancer.
| Variable predictor | RMST Kaplan–Meiera years (95% CI) |
RMST FP Modelb years (95% CI) |
||
|---|---|---|---|---|
| Prognostic Group | A n = 142 |
Gleason score 6 n =127 |
9.92 (9.80–10.03 |
9.97 (9.965–9.964 |
| Gleason of 7 n = 15 |
8.42 | 9.91 (9.89–9.94) |
||
| B n = 53 |
Gleason score 6 n = 37 |
9.67 (9.05–10.29) |
9.26 (9.20–9.33) |
|
| Gleason score of 7 n = 16 |
9.42 (9.09–9.75) |
8.62 (8.14–9.1) |
||
| C n = 54 |
Gleason score 6 n = 33 |
7.11 (6.27–7.95) |
7.11 (6.91–7.31) |
|
| Gleason of 7 n = 21 |
3.07 (2.23–3.90) |
3.79 (3.49–4.08) |
||
% = percentage; CI = confidence interval; ≤ = Equal or less than
a
The RMST is the area under the Kaplan–Meier survival curve, determined by the numerical integration
b
The RMST is the area under the FP survival model. The FP model incorporates: age (continuous variable), prognostic group B (dummy variable), prognostic group C (dummy variable) and Gleason score of 7 (dummy variable) with one degrees of freedom for the restricted cubic spline function used for the baseline hazard rate (DF1) and also consider the dummy variables Gleason score of 7 as variable time-dependent effect using one degree of freedom for its fit in model (DFTVC1)